| Autor: |
Gradiski D, Duprat P, Magadur JL, Poitou P |
| Jazyk: |
francouzština |
| Zdroj: |
Toxicological European research. Recherche europeenne en toxicologie [Toxicol Eur Res] 1979 Mar; Vol. 2 (2), pp. 77-86. |
| Abstrakt: |
The acute effects of two industrial substances were studied in mice, rats, rabbits and guinea pigs: - lethal concentration 50 (L.D. 50) in mice and rats after intraperitoneal and oral administration; - investigation of cell growth inhibition (Hela cells), I.D.50 = inhibitory dose 50%; - neuropharmacological effects Histopathological investigations and biochemical analysis pointed out hepatic and renal damages; besides hematological disturbances were found. Both products had mild irritant effects on rabbits skin and eyes. They produced skin sensitization in guinea pigs. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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