[Toxicity and radioprotective properties of 1,3-oxazine and 1,3-thiazine derivatives].

Autor: Il'iuchenok TIu, Frigidova LM, Shadurskiĭ KS, Lepekhin VP, Ignatova LA
Jazyk: ruština
Zdroj: Farmakologiia i toksikologiia [Farmakol Toksikol] 1979 Nov-Dec; Vol. 42 (6), pp. 643-7.
Abstrakt: Toxicity and radioprotective properties of 18 derivatives of oxazine and thiazine with a varying degree of the cycle saturation were studied in experiments on mice. Monotypic regularity in variations of their toxic properties relative to the chemical structure was noted. 4,4,6-Trimethyl-2-dimethylamino-4H-1,3-oxazine exerted a pronounced radioprotective action.
Databáze: MEDLINE