| Autor: |
Chiarandini DJ, Stefani E |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of physiology [J Physiol] 1974 Jul; Vol. 240 (1), pp. 1-14. |
| DOI: |
10.1113/jphysiol.1974.sp010595 |
| Abstrakt: |
1. The modifications of isometric twitches after K contractures have been studied in single muscle fibres from frog muscles.2. The twitch was greatly enhanced and somewhat prolonged after a conditioning K contracture. This potentiating effect was more evident in fibres having low values of the ratio control twitch tension/tetanus tension (P/P(0)).3. In most of the fibres, the time course of the decay of the potentiation phenomenon could be represented by the sum of three negative exponentials with average half-times of 9.1, 40 and 485 sec.4. Between 3 and 10 min after the onset of the twitch potentiation the resting potential and action potential were unchanged.5. Mn blocked the K contractures and prevented the onset of the twitch potentiation.6. 40-140 sec after inducing a K contracture with 30 or 40 mM-K, a second exposure to the same [K] evoked a tension equivalent only to 57% of the first one. This partial refractoriness of the fibres is not seen when both contractures were elicited with 190 mM-K, and contrasts with the full recovery and potentiation of the twitch after a K contracture. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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