The occurrence of lipidic particles in lipid bilayers as seen by 31P NMR and freeze-fracture electron-microscopy.

Autor: de Kruijff B, Verkley AJ, van Echteld CJ, Gerritsen WJ, Mombers C, Noordam PC, de Gier J
Jazyk: angličtina
Zdroj: Biochimica et biophysica acta [Biochim Biophys Acta] 1979 Aug 07; Vol. 555 (2), pp. 200-9.
DOI: 10.1016/0005-2736(79)90160-3
Abstrakt: A new type of lipid organization is observed in mixtures of phosphatidyl-choline with cardiolipin (in the presence of Ca2+), monoglycosyldiglyceride and phosphatidylethanolamine (in the presence of cholesterol). This phase is characterised by an isotropic 31P NMR signal and is visualised by freeze-fracturing as particles and pits on the fracture faces of the lipid bilayer. As the most favourable model for this phase we propose the inverted micelle sandwiched in between the two monolayers of the lipid bilayer.
Databáze: MEDLINE