[Factor analysis of the effectiveness of combined therapy in experimental leukemia].

Autor: Emanuél' NM, Konovalova NP, Volkova LM, Rusanov VV
Jazyk: ruština
Zdroj: Voprosy onkologii [Vopr Onkol] 1979; Vol. 25 (6), pp. 96-100.
Abstrakt: The effectiveness of the combined therapy of leukemia P-388 with cyclophosphane and diazane was studied. The pattern of administering these substances was selected with due consideration of the cyclospecificity of their action. In a number of cases considerable synergism was observed, resulting in a cure of 100% of animals. Estimation of the effectiveness and the degree of synergism was made by the method of fractionation analysis, which allowed delineating some trends for providing the optimum combined therapy.
Databáze: MEDLINE