Comparison of fluorescent antibody induced by rubella virus in vaccinee and convalescent individuals.

Autor: Serafini A, Cole GC, Brackett RG
Jazyk: angličtina
Zdroj: Applied microbiology [Appl Microbiol] 1972 Jan; Vol. 23 (1), pp. 66-71.
DOI: 10.1128/am.23.1.66-71.1972
Abstrakt: Specific rubella antibody detectable by indirect immunofluorescence developed in response to immunization with attenuated rubella vaccine, HPV-77, DK-12. Fluorescent antibody (FA) was found when vaccinee sera were reacted with antigens synthesized in three different acutely infected continuous cell lines: BHK-21, LLCMK-2, and RK-13. FA titers were high, and they correlated with antibody titers obtained by hemagglutination-inhibition tests. Levels of FA in vaccinated individuals were slightly lower than those found in persons recovered from natural rubella infections. Rubella FA persists a long time in convalescent individuals and appears to be maintained for at least 19 months in vaccinees.
Databáze: MEDLINE