| Autor: |
Groseclose R; Department of Anatomy, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106., Hopfer U |
| Jazyk: |
angličtina |
| Zdroj: |
Membrane biochemistry [Membr Biochem] 1978; Vol. 2 (1), pp. 135-48. |
| DOI: |
10.3109/09687687809063862 |
| Abstrakt: |
The effect of semistarvation on small intestinal transport of D-glucose, L-valine, and NaCl was studied in an in vitro system of isolated rat brush border membrane vesicles. Whereas semistarvation enhanced the transport rate for L-valine by 19-29%, there was no change in D-glucose transport. When energy in the form of a NaSCN gradient was supplied to the membrane vesicles prepared from semistarved animals, L-valine was concentrated to a greater extent than those from well-fed animals. Strain differences were observed in the manner semistarvation affected NaCl transport across the brush border membrane. Semistarvation increased the NaCl transport rate by a factor of 3.5 in one rat strain and not at all in another. These results provide a partial explanation for the cellular basis of elevated neutral amino acid absorption by the small intestine in semistarvation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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