Reactions and serologic responses to monovalent acetone-inactivated typhoid vaccine and heat-killed TAB when given by jet injection.

Autor: Edwards EA, Johnson DP, Pierce WE, Peckinpaugh RO
Jazyk: angličtina
Zdroj: Bulletin of the World Health Organization [Bull World Health Organ] 1974; Vol. 51 (5), pp. 501-5.
Abstrakt: Monovalent acetone-inactivated typhoid vaccine and heat-killed TAB caused local reactions in 82-88% of volunteers vaccinated by jet injection, whereas they caused local reactions in only 24% of volunteers injected by means of a conventional syringe. Both vaccines induced a high seroconversion rate to typhoid H antigen, but neither proved significantly immunogenic to antigens O and Vi. There was no increase in the occurrence of local reactions when a second jet injection was given 5 weeks after the first.
Databáze: MEDLINE