[Lipid peroxidation, peroxidase activity and glutathione antiperoxide systems in rat tissues under conditions of high altitude hypoxia].

Autor: Shafran LM, Gukevich EK, Levitskiĭ AP
Jazyk: ruština
Zdroj: Ukrainskii biokhimicheskii zhurnal (1978) [Ukr Biokhim Zh (1978)] 1979 Mar-Apr; Vol. 51 (2), pp. 107-10.
Abstrakt: The content of lipid peroxides in rat tissues does not vary essentially under conditions of high altitude hypoxia. The peroxidase activity undergoes fluctuating changes with a significant increase in brain tissues. Among the enzymes of the glutathione antiperoxide system only the glutathione peroxidase activity shows a 5-10-fold decrease. As assumption is advanced that under conditions of hypoxia there occurs an inhibition of the glutathione antiperoxide system, which prevents the lipid peroxides level in tissues from falling.
Databáze: MEDLINE