Peroxidatic oxidation of tyrosine to melanin in supernatant of crude mouse melanoma homogenates.

Autor: Patel RP, Okun MR, Edelstein LM, Cariglia N
Jazyk: angličtina
Zdroj: The Biochemical journal [Biochem J] 1974 Aug; Vol. 142 (2), pp. 441-3.
DOI: 10.1042/bj1420441
Abstrakt: Peroxide-dependent enzymic oxidation of tyrosine to dopachrome and melanin was demonstrated in cell-free melanoma homogenates. Histochemical methods for distinguishing peroxidase activity from aerobic dopa (3,4-dihydroxyphenylalanine) oxidase activity are not reliable with cell-free preparations. Therefore the presence of peroxidase activity in such preparations precludes assay of cresolase activity of mammalian ;tyrosinase'.
Databáze: MEDLINE