Autor: |
O'Brien JS, Miller AL, Loverde AW, Veath ML |
Jazyk: |
angličtina |
Zdroj: |
Science (New York, N.Y.) [Science] 1973 Aug 24; Vol. 181 (4101), pp. 753-5. |
DOI: |
10.1126/science.181.4101.753 |
Abstrakt: |
alpha-Acetylglucosaminidase, purified from human placent, corrected the defect in mucopolysaccharide degradation when added to culture fibroblasts from patients with Sanfilippo disease type B. A small cellular concentration of enzyme gave a large corrective effect. The half-life of disappearance of enzyme activity was 4 to 7 days. |
Databáze: |
MEDLINE |
Externí odkaz: |
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