[Role of planar cobalt chelate complexes as shunting agents in the electron transport chain of mitochondria].
| Autor: | Leĭkin IuN, Novodarova GN, Kolosova EM, Vol'pin ME |
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| Jazyk: | ruština |
| Zdroj: | Biokhimiia (Moscow, Russia) [Biokhimiia] 1979 Jan; Vol. 44 (1), pp. 97-103. |
| Abstrakt: | It was shown that planar cobalt chelate complexes catalyze oxidation of NADH and hexahydroubiquinole Q4H2 by air oxygen. The most active agent--perchlorate of the cobalt complex 1, 2, 3, 7, 8, 12, 13, 17, 18, 19-decamethyloctadehydrocorrin--is capable of shunting the electron transfer chain of rat liver mitochondria and beef heart submitochondrial particles, catalyzing electron transfer from CoQ directly to the oxygen. |
| Databáze: | MEDLINE |
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