[Soluble surface antigens of virulent Sh. sonnei].

Autor: Kovalevskaia IL, Shcheglova ES, Iarovaia LM, Korneeva SA, Solov'eva OG
Jazyk: ruština
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1977 Dec (12), pp. 48-54.
Abstrakt: The authors conducted an immunochemical analysis of the surface soluble antigen preparations (SSAP) obtained by extraction with physiological saline of the virulent Sh. sonnei microbes killed with acetone. Immunochemical studies by the immunoelectrophoresis and immunodiffusion methods in agar gel, separation on sepharose 4B and in polyacrylamide gel showed the presence of 3 groups of the antigens in the SSAP composition: 1) protein antigens, determining the commonness with the Sonne microbes of the II phase and intergenera associations with typhoid and enteropathogenic E. coli; 2) specific somatic antigen of the Boiven type present in small amounts in the SSAP; 3) specific antigens differing by specificity from the Boiven antigen detected in the microbes of the I phase only and possibly playing a role in the virulent and immunogenic properties of the causative agent.
Databáze: MEDLINE