| Autor: |
Janssen JT, Ludwig H, Scheithauer W, de Pauw BE, Keyser A, van Tol R, Flener R |
| Jazyk: |
angličtina |
| Zdroj: |
Oncology [Oncology] 1985; Vol. 42 Suppl 1, pp. 3-6. |
| DOI: |
10.1159/000226075 |
| Abstrakt: |
Twenty-two patients with advanced haemopoietic and other malignancies were treated intramuscularly with recombinant interferon-alpha 2C in a daily escalating dose. The most common side-effects were flu-like symptoms. Two patients showed severe neurotoxicity, which was completely reversible in 1 case. Doses above 30 X 10(6) IU/day were poorly tolerated and could only be achieved in a minority of the patients. Objective tumour responses were documented in malignant lymphomas, hairy cell leukaemia, and renal cell carcinoma. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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