Comparison of two calcium antagonists, verapamil and gallopamil (D-600), in exercise-induced asthma.

Autor: Patel KR, Tullett WM
Jazyk: angličtina
Zdroj: European journal of respiratory diseases [Eur J Respir Dis] 1985 Oct; Vol. 67 (4), pp. 269-71.
Abstrakt: The effect of inhaled verapamil and gallopamil (estimated dose 3 mg) was studied in 10 patients with exercise-induced asthma. Saline was used as a control. Verapamil and gallopamil modified exercise-induced asthma in 8 of the 10 patients and the degree of inhibition with both the drugs was comparable. Gallopamil, which is a more potent vascular smooth muscle calcium antagonist when compared to verapamil, failed to show a greater protective effect in exercise-induced asthma in the patients studied.
Databáze: MEDLINE