[Comparative analysis of the malignancy of tumors in mice induced by 20-methylcholanthrene].

Autor: Viksler VKh, Iaroslavtseva OA, Lavroskiĭ VA
Jazyk: ruština
Zdroj: Eksperimental'naia onkologiia [Eksp Onkol] 1985; Vol. 7 (5), pp. 21-4.
Abstrakt: Malignancy of 13 cell cultures cultivated in vitro was studied. 11 cultures were induced by subcutaneous injection of 20-methylcholanthrene to 3 lines of mice. The malignancy was studied by transplantability, growth rate and metastasis formation after subcutaneous injection of a various cell number into normal and sublethally irradiated syngenic mice. A convenient model for studying the significance of certain immunological properties of tumour cells in determination of the malignancy was obtained.
Databáze: MEDLINE