Autor: |
Gendenshteĭn EI, Volkova ND, Oleĭnikova EA, Novikova LV |
Jazyk: |
ruština |
Zdroj: |
Farmakologiia i toksikologiia [Farmakol Toksikol] 1977 Mar-Apr; Vol. 40 (2), pp. 174-7. |
Abstrakt: |
Tests conducted with 125 cats demonstrated that occlusion of the coronary artery causes a higher sensitivity to the bathmotropic action of strophanthin, but does not have any effect on the magnitude of its lethal dose. The efficaciousness of potassium orotate and also of Na2EDTA in combinations with anapriline and isadrine, as regulators of the sensitivity to the toxic effect of strophanthin, was investigated. Immunization of cats with a homocardiac antigen was found to produce biphasic changes in the sensitivity to the toxic effect of strophanthin associated with the duration of antigenic stimulation. |
Databáze: |
MEDLINE |
Externí odkaz: |
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