[The role of erythrocyte deformability in the prolonged bleeding time in liver disease patients].

Autor: Moia M, Mari D, Coccato MP, Della Valle P, Tripodi A, Mannucci PM
Jazyk: italština
Zdroj: La Ricerca in clinica e in laboratorio [Ric Clin Lab] 1985; Vol. 15 Suppl 1, pp. 213-8.
Abstrakt: Hematocrit (Ht), red cell deformability (RCD) determined using a filtration method and bleeding time (BT) have been studied in 28 patients with severe chronic liver disease. Our results show a decrease of Ht (p less than 0.001), RCD (p less than 0.05) and a prolongation of BT (p less than 0.001) not related to the platelet count. Moreover, inverse relationships between Ht and BT (r = -0.52; p less than 0.01) and between RCD and BT (r = -0.54; p less than 0.01) have been found. We conclude that hemorheological alterations, such as decreased Ht and RCD, play an important role in primary hemostasis of patients with chronic liver disease.
Databáze: MEDLINE