Disulfiram hepatitis.

Autor: Morris SJ; Department of Medicine, Veterans Administration Hospital, Miami, Florida 33125., Kanner R, Chiprut RO, Schiff ER
Jazyk: angličtina
Zdroj: Gastroenterology [Gastroenterology] 1978 Jul; Vol. 75 (1), pp. 100-2.
Abstrakt: A case of an adult with disulfiram-induced hepatitis is presented. An etiological role for the drug was proved when the patient underwent a provocative challenge and developed evidence of hepatocellular damage, reversible on withdrawal of the drug. Disulfiram-induced liver injury is difficult to detect in a population with a high incidence of alcohol-related hepatic disease. Liver chemistries should be screened before beginning disulfiram therapy and periodically during treatment.
Databáze: MEDLINE