Serotonin receptors on pulmonary alveolar macrophages.
| Autor: | Essman EJ |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | La Ricerca in clinica e in laboratorio [Ric Clin Lab] 1985 Jan-Mar; Vol. 15 (1), pp. 19-24. |
| DOI: | 10.1007/BF03029157 |
| Abstrakt: | Pulmonary alveolar macrophages harvested from the albino mouse lung were shown to possess surface receptor sites capable of binding physiological concentrations of serotonin (5-hydroxytryptamine). These specific, high affinity binding sites showed temperature-dependent kinetics with a single order high affinity binding site for serotonin. The presence of serotonin receptors on pulmonary alveolar macrophages provides a basis for relating at least one mediator of pulmonary inflammatory processes and transport processes to effects upon the macrophage surface. |
| Databáze: | MEDLINE |
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