The effect of a diuretic (hydrochlorothiazide) on tear production in humans.

Autor: Bergmann MT, Newman BL, Johnson NC Jr
Jazyk: angličtina
Zdroj: American journal of ophthalmology [Am J Ophthalmol] 1985 Apr 15; Vol. 99 (4), pp. 473-5.
DOI: 10.1016/0002-9394(85)90016-9
Abstrakt: The effect of an orally administered diuretic, hydrochlorothiazide, on tear production in 11 normal young human subjects (five men and six women, 18 to 35 years old) was measured in a single-masked study. Schirmer tests with topical anesthetic showed a significant (P = .02) decrease in basal aqueous tear production on days when these subjects were taking the diuretic. The average decrease was 2.1 mm of wetting in five minutes.
Databáze: MEDLINE