Synthesis and antimicrobial action of some bis-thiazolidines.

Autor: Salama HM, Vladzimirska HV, Turkevich NM, Stebljuk PN
Jazyk: angličtina
Zdroj: Die Pharmazie [Pharmazie] 1979 Nov; Vol. 34 (11), pp. 720-1.
Abstrakt: alpha, delta-Bis(thiazolidinidione-2,4-hydrazone-4-yl-3)butane (1) was reacted with heterocyclic and aromatic aldehydes in boiling glacial acetic acid, where the corresponding analogs of alpha, delta-bis (thiazolidindione-2,4-N-arylidenehydrazone-4-yl-3)butane (2) were separated. While with some other heterocyclic and aromatic aldehydes, and under the same conditions, the corresponding analogs of alpha, delta-bis(thiazolidinidione-2,4-N-arylidenehydrazone-4-arylidene-5-yl-3) butane (3) were obtained. The synthesized compounds exhibit antimicrobial activity.
Databáze: MEDLINE