Modulating synaptic plasticity with metal-organic framework for information-filterable artificial retina.

Autor: Kim S; Department of Electrical and Systems Engineering, University of Pennsylvania, Philadelphia, PA, USA., Kwon O; Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, Republic of Korea.; Department of Chemistry, University of California, Berkeley, CA, USA., Kim S; Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, Republic of Korea., Jang S; Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, Pennsylvania, PA, USA., Yu S; Department of Chemical Engineering, Konkuk University, Seoul, Republic of Korea., Lee CH; Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, Republic of Korea., Choi YY; Department of Mechanical Science and Engineering, University of Illinois, Urbana-Champaign, Urbana, IL, USA., Cho SY; Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, Republic of Korea., Kim KC; Department of Chemical Engineering, Konkuk University, Seoul, Republic of Korea.; Division of Chemical Engineering, Konkuk University, Seoul, Republic of Korea., Yu C; Department of Mechanical Science and Engineering, University of Illinois, Urbana-Champaign, Urbana, IL, USA. cunjiang@illinois.edu.; Department of Electrical and Computer Engineering, University of Illinois, Urbana-Champaign, Urbana, IL, USA. cunjiang@illinois.edu.; Department of Materials Science and Engineering, University of Illinois, Urbana-Champaign, Urbana, IL, USA. cunjiang@illinois.edu.; Department of Bioengineering, University of Illinois, Urbana-Champaign, Urbana, IL, USA. cunjiang@illinois.edu.; Materials Research Laboratory, University of Illinois, Urbana-Champaign, Urbana, IL, USA. cunjiang@illinois.edu.; Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana-Champaign, Urbana, IL, USA. cunjiang@illinois.edu.; Nick Holonyak Micro and Nanotechnology Laboratory, University of Illinois, Urbana-Champaign, Urbana, IL, USA. cunjiang@illinois.edu., Kim DW; Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, Republic of Korea. audw1105@yonsei.ac.kr., Cho JH; Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, Republic of Korea. jhcho94@yonsei.ac.kr.
Jazyk: angličtina
Zdroj: Nature communications [Nat Commun] 2025 Jan 02; Vol. 16 (1), pp. 162. Date of Electronic Publication: 2025 Jan 02.
DOI: 10.1038/s41467-024-55173-2
Abstrakt: Neuroprosthetics equipped with artificial synapses hold promise to address some most intricate medical problems, such as human sensory disorders. Yet, it is necessitated and of paramount importance for neuroprosthetics to be able to differentiate significant and insignificant signals. Here, we present an information-filterable artificial retina system that integrates artificial synapses with a signal-integration device for signal perception and processing with attention. The synaptic weight modulation is rendered through metal-organic framework (MOF) layers, where distinct short-term and long-term properties are predominantly determined by MOF's pore diameter and functionality. Specifically, four types of isoreticular Zr-based MOFs that share Zr 6 O 4 (OH) 4 secondary building units have been systematically examined. It is demonstrated that small pore diameters enhance short-term properties, while large pores, which are characterized by increased ion affinity, sustain long-term properties. Moreover, we demonstrated a 6 × 6 pixel artificial retina by incorporating both short-term and long-term artificial synapses with a signal-integration device. Signal summation by the signal-integration device enables attention-based information processing. The information-filterable artificial retina system developed here emulates human perception processes and holds promise in the fields of neuroprosthetics and advanced artificial intelligence.
Competing Interests: Competing interests: The authors declare no competing interests.
(© 2024. The Author(s).)
Databáze: MEDLINE
Externí odkaz: