Influence of the combination of mineral water and ciprofloxacin on the interaction form of individual representatives of the upper respiratory tract mucosa microbiota in vitro .

Autor:	Rusakova M; Department of Microbiology, Virology and Biotechnology, State Institute Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy, Ministry of Health, Kyiv, Ukraine.; I. I. Mechnikov National University, Odessa, Ukraine., Gushcha S; Department of Fundamental Research, State Institute Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy of the Ministry of Health, Odessa, Ukraine., Sierpińska LE; Independent Public Health Care Unit, Military Clinical Hospital No. 1 with Polyclinic, Lublin, Poland.; Higher School, Radom, Poland.; Vincent Pol University, Lublin, Poland., Koieva K; Strategies and Programmess, State Institute Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy of the Ministry of Health, Odessa, Ukraine.
Jazyk:	angličtina
Zdroj:	Annals of agricultural and environmental medicine : AAEM [Ann Agric Environ Med] 2024 Dec 22; Vol. 31 (4), pp. 492-496. Date of Electronic Publication: 2024 Oct 02.
DOI:	10.26444/aaem/193429
Abstrakt:	Introduction and Objective: Elimination irrigation therapy has been proposed as a potential treatment for upper respiratory tract infections, particularly after the COVID-19 pandemic, due to its antiviral properties and mechanical cleansing effects. Additionally, a combination of mineral water with antibiotic therapy has shownto be effective in improving the course clinical infection and positively impact the immune system, potentially enhancing the normal state of microbiota state. The aim of the study is to investigate the influence of elimination-irrigation therapy using a combination of mineral water and ciprofloxacin on the interaction form of individual microbiota species of the upper respiratory tract mucous membrane. Material and Methods: During the study, microbiological methods were used, such as microscopic, bacteriological and biofilm cultivation methods. rovoking antagonistic interactions within these associations, and a general decrease in microbial colonization activity. During the multispecies biofilm formation by L. sporogenes and S. aureus ATCC 25923, as well as L. sporogenes and E. coli ATCC 25922, a mutual antagonistic effect was determined. The forms of microbial interaction in multispecies biofilm was changed in the presence of 0.0313 mg/ml Ciprofloxacin. Conclusions: The 10-minute mineral water treatment and addition of 0.0313 mg/ml Ciprofloxacin enhanced the antagonistic interaction between L. sporogenes and E. coli ATCC 25922, as well as with S. aureus ATCC 25923.
Databáze:	MEDLINE
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