Mechanical Circulatory Support for Right Ventricular Primary Graft Dysfunction After Heart Transplant: A Review.

Autor: Hart EA; Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands., Braithwaite SA; Department of Anesthesiology, University Medical Center Utrecht, Utrecht, Netherlands., Hermens JAJ; Department of Intensive Care, University Medical Center Utrecht, Utrecht, Netherlands., Kraaijeveld AO; Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands., Ramjankhan F; Department of Cardiothoracic Surgery, University Medical Center Utrecht, Utrecht, Netherlands., van Laake LW; Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands., Oerlemans MIFJ; Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands., Szymanski MK; Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Jazyk: angličtina
Zdroj: Clinical transplantation [Clin Transplant] 2025 Jan; Vol. 39 (1), pp. e70066.
DOI: 10.1111/ctr.70066
Abstrakt: Primary graft dysfunction (PGD) is the most common cause of early mortality following heart transplantation. Although PGD can affect both ventricles, isolated right ventricular dysfunction (RV-PGD) is observed in nearly half of PGD patients. RV-PGD requires specific medical management to support the preload, afterload, and function of the failing RV; however, the use of mechanical circulatory support of the RV (RV-MCS) might be required when optimal medical therapy is insufficient in preventing forward failure and retrograde venous congestion. While RV-MCS options provide the opportunity to prevent or to recover from circulatory shock states, MCS is associated with a significant risk of complications. As a result of recent developments in short-term mechanical support devices, less invasive, percutaneous options for RV-MCS are available. In this review, we discuss the available devices, their advantages and disadvantages, and reported outcomes in RV-PGD.
(© 2024 The Author(s). Clinical Transplantation published by Wiley Periodicals LLC.)
Databáze: MEDLINE