Impact of socioeconomic and geographical factors on clinical care of biliary atresia patients: a cross-sectional study.

Autor: Singhai P; Department of Pediatric Surgery, Advanced Pediatric Centre, PGIMER, Block 5D, Room No 5422, 5th Floor, Sector 12, Chandigarh, 160012, India., Solanki S; Department of Pediatric Surgery, Advanced Pediatric Centre, PGIMER, Block 5D, Room No 5422, 5th Floor, Sector 12, Chandigarh, 160012, India. drshaileshpgi@gmail.com., Kanojia RP; Department of Pediatric Surgery, Advanced Pediatric Centre, PGIMER, Block 5D, Room No 5422, 5th Floor, Sector 12, Chandigarh, 160012, India., Peters NJ; Department of Pediatric Surgery, Advanced Pediatric Centre, PGIMER, Block 5D, Room No 5422, 5th Floor, Sector 12, Chandigarh, 160012, India., Kiran CS; Department of Pediatric Surgery, Advanced Pediatric Centre, PGIMER, Block 5D, Room No 5422, 5th Floor, Sector 12, Chandigarh, 160012, India., Gupta PK; Department of Biostatistics, PGIMER, Chandigarh, India., Lal SB; Department of Gastroenterology, Pediatric Division, PGIMER, Chandigarh, India., Mahajan JK; Department of Pediatric Surgery, Advanced Pediatric Centre, PGIMER, Block 5D, Room No 5422, 5th Floor, Sector 12, Chandigarh, 160012, India.
Jazyk: angličtina
Zdroj: Pediatric surgery international [Pediatr Surg Int] 2024 Dec 30; Vol. 41 (1), pp. 53. Date of Electronic Publication: 2024 Dec 30.
DOI: 10.1007/s00383-024-05949-w
Abstrakt: Purpose: Biliary atresia (BA) is a critical pediatric condition requiring timely intervention through Kasai portoenterostomy (KPE), and up to two-thirds of patients need liver transplantation (LT). The outcomes for BA patients still need improvement in low- and middle-income countries. This study aims to assess the socioeconomic and geographical profile of BA patients in India, focusing on their compliance with follow-up care, treatment-seeking behaviour, and acceptability of LT in addition, it provides recommendations to overcome identified challenges.
Methods: A retrospective observational study was conducted in a tertiary care centre in India, including 48 patients who underwent KPE between 2018 and 2022. SES was assessed using the modified Kuppuswamy scale, and geographical areas were classified as per the criteria of the Indian Census 2011. Compliance with follow-up, treatment-seeking behaviour, and LT acceptability were evaluated.
Results: The majority of patients belonged to rural areas and lower middle SES. Compliance with follow-up decreased over time, with financial and geographical barriers being significant challenges. Only one patient underwent LT due to prohibitive costs and limited accessibility.
Conclusion: Socioeconomic and geographical factors significantly impact the clinical outcomes of BA patients in India. Improving education, healthcare infrastructure, and financial support is crucial for enhancing patient compliance and access to necessary treatments.
Competing Interests: Declarations. Conflict of interest: The authors declare no competing interests. Ethical approval: Institute ethical clearance–yes.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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