Identifying early left atrial dysfunction in COPD patients using ECG morphology-voltage-P wave duration score.

Autor: Küçük U; Department of Cardiology, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey. Electronic address: drugurkucuk@hotmail.com., Mutlu P; Department of Chest Diseases, Faculty of Medicine, Çanakkale Onsekiz Mart University, Canakkale, Turkey., Mirici A; Department of Chest Diseases, Faculty of Medicine, Çanakkale Onsekiz Mart University, Canakkale, Turkey., Özpınar U; Department of Cardiology, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey., Özpınar SB; Department of Chest Diseases, Faculty of Medicine, Çanakkale Onsekiz Mart University, Canakkale, Turkey.
Jazyk: angličtina
Zdroj: Journal of electrocardiology [J Electrocardiol] 2024 Dec 19; Vol. 88, pp. 153854. Date of Electronic Publication: 2024 Dec 19.
DOI: 10.1016/j.jelectrocard.2024.153854
Abstrakt: Background: Chronic Obstructive Pulmonary Disease (COPD) is associated with left atrial (LA) dyfunction, which may contribute to adverse cardiovascular outcomes. This study investigates the predictive value of lately identified morphology-voltage-P wave duration electrocardiography (MVP ECG) score for detecting early LA dysfunction in COPD patients.
Methods: In this cross-sectional study, 101 COPD patients were enrolled. All patients underwent speckle tracking echocardiography and were classified into two groups based on their LA functions.
Results: Our findings demonstrate significant variations in Peak Atrial Longitudinal Strain (PALS) values among COPD patients, with a mean PALS of 28.74 ± 1.81 % for the group with normal LA function and 18.44 ± 1.87 % for the group with abnormal LA function (p < 0.001). Despite similar LA diameters across groups, these variations indicate subclinical LA pathogenesis. ROC curve analysis indicated that an MVP ECG score greater than 2.5 predicted abnormal LA function with a sensitivity of 65 % and a specificity of 91 % (area under the curve [AUC]: 0.873; p < 0.001), suggesting its utility in identifying atrial damage and remodeling.
Conclusions: The MVP ECG score shows promise as a tool for early detection of atrial remodeling in COPD patients.
Competing Interests: Declaration of competing interest No conflict of interest was declared by the authors.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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