Cancer genetic counseling in Chile: Addressing barriers, confronting challenges, and seizing opportunities in an underserved Latin American Community.

Autor:	Fernández-Ramires R; Facultad de Medicina y Ciencias de la Salud. Universidad Mayor. Santiago, Chile.; Grupo Chileno de Cáncer Hereditario (GCCH), Santiago, Chile., Morales-Pison S; Facultad de Medicina y Ciencias de la Salud. Universidad Mayor. Santiago, Chile.; Grupo Chileno de Cáncer Hereditario (GCCH), Santiago, Chile., Rucatti GG; Facultad de Medicina y Ciencias de la Salud. Universidad Mayor. Santiago, Chile.; Grupo Chileno de Cáncer Hereditario (GCCH), Santiago, Chile., Echeverría C; Grupo Chileno de Cáncer Hereditario (GCCH), Santiago, Chile.; ATACAMA-OMICS, Facultad de Medicina. Universidad de Atacama. Copiapó, Chile., San Martín E; Grupo Chileno de Cáncer Hereditario (GCCH), Santiago, Chile.; Hospital Clínico Regional de Concepción Guillermo Grant Benavente. Concepción, Chile., Cammarata-Scalisi F; Grupo Chileno de Cáncer Hereditario (GCCH), Santiago, Chile.; Hospital Regional de Antofagasta. Antofagasta, Chile., Salas-Burgos A; Grupo Chileno de Cáncer Hereditario (GCCH), Santiago, Chile.; Departamento de Farmacología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile., Adorno-Farias D; Grupo Chileno de Cáncer Hereditario (GCCH), Santiago, Chile.; Facultad de Odontología. Universidad de Chile, Santiago, Chile., González-Arriagada WA; Grupo Chileno de Cáncer Hereditario (GCCH), Santiago, Chile.; Facultad de Odontología, Universidad de los Andes, Santiago, Chile., Espinosa-Parrilla Y; Grupo Chileno de Cáncer Hereditario (GCCH), Santiago, Chile.; Genómica Evolutiva y Médica de Magallanes (GEMMa), Centro Asistencial, Docente e Investigación (CADI-UMAG), Universidad de Magallanes, Punta Arenas, Chile.; Escuela de Medicina, Universidad de Magallanes, Punta Arenas, Chile., Zapata-Contreras D; Grupo Chileno de Cáncer Hereditario (GCCH), Santiago, Chile.; Genómica Evolutiva y Médica de Magallanes (GEMMa), Centro Asistencial, Docente e Investigación (CADI-UMAG), Universidad de Magallanes, Punta Arenas, Chile.; Escuela de Medicina, Universidad de Magallanes, Punta Arenas, Chile., Norese G; Universidad de Buenos Aires, Escobar, Argentina., Lázaro C; Programa de Cáncer Hereditario. Instituto Catalán de Oncología. Barcelona, Spain., González S; Programa de Cáncer Hereditario. Instituto Catalán de Oncología. Barcelona, Spain., Pujana MA; ProCURE, Instituto Catalán de Oncología, Instituto de Investigación Biomédica Bellvitge (IDIBELL), Barcelona, España., Sullcahuaman Y; Instituto Nacional de Enfermedades Neoplasicas (INEN). Lima, Perú., Margarit S; Grupo Chileno de Cáncer Hereditario (GCCH), Santiago, Chile.; Clínica Alemana, Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile.
Jazyk:	angličtina
Zdroj:	Genetics in medicine open [Genet Med Open] 2024 Oct 30; Vol. 2 (Suppl 2), pp. 101898. Date of Electronic Publication: 2024 Oct 30 (Print Publication: 2024).
DOI:	10.1016/j.gimo.2024.101898
Abstrakt:	Purpose: Despite the rapid advancements in genomics and the enactment of a new cancer law in Chile, the implementation of cancer genetic counseling continues to face significant challenges because of limited resources and infrastructure. Methods: We conducted a survey targeting health care providers who offer genetic counseling to patients with cancer and possess training in genetics and counseling. Additionally, we distributed a separate survey to high-risk patients associated with an advocacy group to gather insights on their perceptions of and experiences with cancer genetic counseling. Results: Among the surveyed providers, 21% were nonmedical professionals who developed their skills through postgraduate continuing education programs. Germline testing was not performed in 47% of cases. Among the participants, 37% considered genetic counseling important for understanding the cause of their cancer, 25% valued knowing their risk of developing future tumors, and 33% believed it would benefit their current cancer treatment. Just over half of the patients (54%) had access to genetic counseling. Among those that received genetic counseling, 85% found it beneficial. Conclusion: In Chile, barriers to genetic counseling persist, particularly in rural areas and because of a shortage of trained professionals. Public policies recognizing genetic counseling's importance are crucial, along with expanding training and infrastructure. Understanding patient perceptions and increasing the number of trained genetic counseling into cancer care, educating clinicians, and advocating for increased access are key steps for enhancing cancer treatment effectiveness in Chile. Competing Interests: The authors declare no conflicts of interest. (© 2024 The Authors.)
Databáze:	MEDLINE
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