The role of reproductive tract microbiota in gynecological health and diseases.

Autor: Wang Z; Department of gynaecology, Gynecological Diagnosis and Treatment Center, Affliated Hospital of Changchun University of Chinese Medicine, No.2, Shenzhen Street, Changchun city, Jilin Province 130000, China., Zhang L; Department of gynaecology, Gynecological Diagnosis and Treatment Center, Affliated Hospital of Changchun University of Chinese Medicine, No.2, Shenzhen Street, Changchun city, Jilin Province 130000, China., Liu X; Department of gynaecology and obstetrics, Gynecological Diagnosis and Treatment Center, Affliated Hospital of Changchun University of Chinese Medicine, No.2, Shenzhen Street, Changchun city, Jilin Province 130000, China., Xu L; Department of gynaecology and obstetrics, Gynecological Diagnosis and Treatment Center, Affliated Hospital of Changchun University of Chinese Medicine, No.2, Shenzhen Street, Changchun city, Jilin Province 130000, China. Electronic address: 974929792@qq.com.
Jazyk: angličtina
Zdroj: Journal of reproductive immunology [J Reprod Immunol] 2024 Dec 15; Vol. 167, pp. 104418. Date of Electronic Publication: 2024 Dec 15.
DOI: 10.1016/j.jri.2024.104418
Abstrakt: The reproductive tract, as a lumen connected to the outside world, its microbial community is influenced by various factors. The changes in its microbiome are closely related to women's health. The destruction of the micro ecological environment will lead to various infections, such as Bacterial vaginosis, sexually transmitted infections, adverse pregnancy outcomes, infertility and tumors. In recent years, with the continuous development and progress of molecular biology, research on reproductive tract microbiota has become a clinical hotspot. The reproductive tract microbiota is closely related to the occurrence and development of female reproductive tract diseases such as vaginitis, pelvic inflammation, PCOS, cervical lesions, and malignant tumors. This article reviews the research on the relationship between vaginal microbiota and female reproductive tract diseases, in order to provide theoretical basis for the prevention and treatment of female reproductive tract diseases.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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