Comparative effectiveness of non-pharmacological therapies for postoperative cognitive dysfunction: Protocol for a systematic review and network meta-analysis.

Autor:	Wu K; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Research Center, Chengdu, China., Bao Q; Department of traditional Chinese medicine, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China., Huang J; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China., Sun S; First Teaching Hospital of Tianjin University Chinese Medicine, Tianjin, China., Li Y; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China., Zhang X; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Research Center, Chengdu, China., Xia M; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Research Center, Chengdu, China., Chen Z; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Research Center, Chengdu, China., Yao J; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Research Center, Chengdu, China., Zhong W; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Research Center, Chengdu, China., Yin Z; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Research Center, Chengdu, China., Liang F; Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.; Sichuan Provincial Acupuncture Clinical Research Center, Chengdu, China.
Jazyk:	angličtina
Zdroj:	PloS one [PLoS One] 2024 Dec 19; Vol. 19 (12), pp. e0309605. Date of Electronic Publication: 2024 Dec 19 (Print Publication: 2024).
DOI:	10.1371/journal.pone.0309605
Abstrakt:	Introduction: Postoperative cognitive dysfunction (POCD) is a common complication following surgery. Electroacupuncture (EA), manual acupuncture (MA), transcutaneous electrical acupoint stimulation (TEAS), and cognitive training (CT) can effectively maintain or improve the postoperative cognitive function of patients. However, it remains unclear which therapy is the most effective. Therefore, this network meta-analysis aims to compare and rank the efficacy of these non-pharmacological therapies for POCD to identify the optimal therapy. Methods and Analysis: A systematic search will be conducted across seven databases (PubMed, Cochrane Library, EMBASE, Web of Science, CINAHL, AMED, and PsycINFO) for articles published between January 2000 and November 2023. Two reviewers will independently conduct study selection and data extraction. The primary outcome will be the changes in the overall cognitive function before and after the intervention. The secondary outcome will be the incidence of POCD. The risk of bias will be assessed using the revised Risk of Bias Assessment Tool. Pairwise and Bayesian network meta-analyses will be performed using RevMan, STATA, and Aggregate Data Drug Information System statistical software. Additionally, the quality of evidence will be assessed using the Grading of Recommendations Assessment, Development, and Evaluation guidelines. Ethics and dissemination: The results will be disseminated to peer-reviewed journals or conferences. Trial Registration: PROSPERO registration number: CRD42023454028. Competing Interests: The authors have declared that no competing interests exist. (Copyright: © 2024 Wu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu