Position Paper on the Treatment of Eosinophilic Esophagitis With Dupilumab.

Autor: Tomás-Pérez M; Allergy Department, Hospital Universitario La Paz, Madrid, Spain.; Instituto de Investigación (IDiPAZ), Madrid, Spain.; SEAIC Food Committee, Eosinophilic Esophagitis Group, Spain., Domenech-Witek J; SEAIC Food Committee, Eosinophilic Esophagitis Group, Spain.; Allergy Department, Hospital Universitario Puerta del Mar, Cádiz, Spain., Ávila-Castellano MR; SEAIC Food Committee, Eosinophilic Esophagitis Group, Spain.; Allergy Department, Hospital Universitario Virgen del Rocío, Sevilla, Spain.; Unidad de Gestión Clínica Alergología, Hospital Universitario Virgen del Rocío, Sevilla, Spain., Carballas-Vázquez C; SEAIC Food Committee, Eosinophilic Esophagitis Group, Spain.; Allergy Department, Complejo Hospitalario Universitario A Coruña, A Coruña, Spain., Vásquez-Bautista AA; SEAIC Food Committee, Eosinophilic Esophagitis Group, Spain.; Allergy Department, Hospital Universitario Puerta de Hierro, Madrid, Spain., Jover-Cerdá V; SEAIC Food Committee, Eosinophilic Esophagitis Group, Spain.; Allergy Department, Hospital General Universitario, Elda, Alicante, Spain., González-Mendiola R; SEAIC Food Committee, Eosinophilic Esophagitis Group, Spain.; Allergy Department, Hospital Central Cruz Roja, Madrid, Spain.
Jazyk: angličtina
Zdroj: Journal of investigational allergology & clinical immunology [J Investig Allergol Clin Immunol] 2024 Dec 19, pp. 0. Date of Electronic Publication: 2024 Dec 19.
DOI: 10.18176/jiaci.1038
Abstrakt: Eosinophilic esophagitis (EoE) is a chronic allergic condition affecting the esophagus and driven by food antigens. Many individuals diagnosed with EoE have other allergic conditions, such as food allergy, asthma, allergic rhinitis, and atopic dermatitis. The clinical goals of therapy in EoE include symptomatic, histologic, and endoscopic remission. The current paradigm for the treatment of EoE in Spain includes proton pump inhibitors, swallowed topical corticosteroids, and food elimination diets. These treatments have proven very effective in clinical studies. In April 2024, the Spanish Agency for Medicines and Medical Products approved dupilumab as the second drug for the treatment of EoE, thus adding this biologic to the therapeutic arsenal in EoE. The present review includes a positioning statement by the authors, all of whom are members of the Spanish Society of Allergy and Clinical Immunology Food-EoE Working Group.
Databáze: MEDLINE