Caregiver worry about COVID-19 as a predictor of social mitigation behaviours and SARS-CoV-2 infection in a 12-city U.S. surveillance study of households with children.

Autor:	Brunwasser SM; Rowan University, 201 Mullica Hill Road, Glassboro, NJ 08033, USA., Gebretsadik T; Vanderbilt University Medical Center, 2525 West End Avenue, Nashville, TN 37203, USA., Satish A; Rowan University, 201 Mullica Hill Road, Glassboro, NJ 08033, USA., Cole JC; Vanderbilt University, 2201 West End Avenue, Nashville, TN 37203, USA., Dupont WD; Vanderbilt University Medical Center, 2525 West End Avenue, Nashville, TN 37203, USA., Joseph C; Henry Ford Hospital Public Health Sciences, Suite 3E, One Ford Place, Detroit, MI 48202, USA., Bendixsen CG; National Farm Medicine Center, Marshfield Clinic Research Institute, 1000 N. Oak Ave. ML-8, Marshfield, WI 54449, USA., Calatroni A; Rho, Inc., 2635 E NC Hwy 54, Durham, North Carolina, 27713, USA., Arbes SJ Jr; Rho, Inc., 2635 E NC Hwy 54, Durham, North Carolina, 27713, USA., Fulkerson PC; Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Sanders J; Rho, Inc., 2635 E NC Hwy 54, Durham, North Carolina, 27713, USA., Bacharier LB; Vanderbilt University Medical Center, 2525 West End Avenue, Nashville, TN 37203, USA., Camargo CA Jr; Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Johnson CC; Henry Ford Health, Detroit, MI, 48202, USA., Furuta GT; Children's Hospital Colorado, Aurora, CO, 80045, USA.; University of Colorado School of Medicine, Aurora, CO, 80045, USA., Gruchalla RS; University of Texas Southwestern Medical Center, Dallas, TX, 75235, USA., Gupta RS; Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Khurana Hershey GK; Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA., Jackson DJ; School of Medicine and Public Health, Univ. of Wisconsin, Madison, WI 53706, USA., Kattan M; Columbia University, New York City, New York, 10024, USA., Liu A; Children's Hospital Colorado, Aurora, CO, 80045, USA., O'Connor GT; Boston University School of Medicine, Boston, MA, 02118, USA., Rivera-Spoljaric K; The Washington University School of Medicine, St Louis, MO, 63110-1010, USA., Phipatanakul W; Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Rothenberg ME; Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA., Seibold MA; National Jewish Health, 1400 Jackson St, Denver, CO, 80206, USA., Seroogy CM; School of Medicine and Public Health, Univ. of Wisconsin, Madison, WI 53706, USA., Teach SJ; Children's National Hospital, Washington, DC, 20010, USA., Zoratti EM; Henry Ford Health, Detroit, MI, 48202, USA., Togias A; Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Hartert TV; Vanderbilt University Medical Center, 2525 West End Avenue, Nashville, TN 37203, USA.
Jazyk:	angličtina
Zdroj:	Preventive medicine reports [Prev Med Rep] 2024 Nov 27; Vol. 49, pp. 102936. Date of Electronic Publication: 2024 Nov 27 (Print Publication: 2025).
DOI:	10.1016/j.pmedr.2024.102936
Abstrakt:	Objective: Understanding compliance with COVID-19 mitigation recommendations is critical for informing efforts to contain future infectious disease outbreaks. This study tested the hypothesis that higher levels of worry about COVID-19 illness among household caregivers would predict lower (a) levels of overall and discretionary social exposure activities and (b) rates of household SARS-CoV-2 infections. Methods: Data were drawn from a surveillance study of households with children ( N  = 1913) recruited from 12 U.S. cities during the initial year of the pandemic and followed for 28 weeks (data collection: 1-May-2020 through 22-Feb-2021). Caregivers rated how much they worried about family members getting COVID-19 and subsequently reported household levels of outside-the-home social activities that could increase risk for SARS-CoV-2 transmission at 14 follow-ups. Caregivers collected household nasal swabs on a fortnightly basis and peripheral blood samples at study conclusion to monitor for SARS-CoV-2 infections by polymerase chain reaction and serology. Primary analyses used generalized linear and generalized mixed-effects modelling. Results: Caregivers with high enrollment levels of worry about COVID-19 illness were more likely to reduce direct social contact outside the household, particularly during the U.S.'s most deadly pandemic wave. Households of caregivers with lower COVID-19 worry had higher odds of (a) reporting discretionary outside-the-home social interaction and (b) SARS-CoV-2 infection. Conclusions: This was, to our knowledge, the first study showing that caregiver COVID-19 illness worry was predictive of both COVID-19 mitigation compliance and laboratory-determined household infection. Findings should inform studies weighing the adaptive value of worrying about infectious disease outbreaks against established detrimental health effects. Competing Interests: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:Unlabelled TableAuthor InitialsRoyalties or LicensesConsulting FeesPayment/honoraria for lectures, presentations, speakers bureaus, manuscript writing, or educational eventsPayment for Expert testimonyStock or stock optionsPatents planned, issued or pendingReceipt of equipment, materials, drugs, medical writing, gifts or other servicesData Safety Monitoring Board MemberDJJAreteia, Avillion, AstraZeneca, GlaxoSmithKline, Genentech, Regeneron, and SanofiPfizerLBBElsevierSanofi, Regeneron, Genentech, GlaxoSmithKline, DBV technologies, Teva, Medscape, Kinaset, OM Pharma, AstraZeneca, and RecludixSanofi, Regeneron, GlaxoSmithKlineSanofi/RegeneronDBV Technologies, AstraZeneca, Vertex, AravaxMERUptoDate,Ception Therapeutics (Reslizumab), Mapi Trust (PEESS instrument)Bristol Myers Squibb,Regeneron/Sanofi,Astra Zeneca,Nexstone One,Celldex,Revolo Biotherapeutics,GuidepointTucker EllisPulm One,Spoon Guru,ClostraBio,Serpin Pharm,Allakos,Celldex,Nextstone One, Santa Ana BioEoE Diagnostic Panel; U.S. Patent 9,345,763MASSpeaker with Honoraria: Rutgers University, (Denver Allergy Rounds, National Jewish Health), Johns Hopkins University, Colorado Allergy and Asthma Society MeetingRGuptaGenentech, Novartis, Aimmune LLC, Allergenis LLC, Food Allergy Research & EducationPatent: Yobee (U.S. Patent No. 11,103,544)SJTUptoDate IncTVHSanofi, Infectious Diseases Respiratory ForumPfizerWPRegeneron, Sanofi, Genentech, Novartis, GSK, Astra Zeneca (© 2024 The Authors.)
Databáze:	MEDLINE
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