| Autor: |
Iqbal S; College of Pharmacy, Al-Ain University, Abu Dhabi Campus, Abu Dhabi, United Arab Emirates., Ahmad AMR; Department of Nutrition & Dietetics, National University of Medical Sciences, Rawalpindi, Pakistan., Abid J; Department of Nutrition & Dietetics, National University of Medical Sciences, Rawalpindi, Pakistan., Qudah T; College of Pharmacy, Al-Ain University, Abu Dhabi Campus, Abu Dhabi, United Arab Emirates., Al-Dabbas MM; College of Pharmacy, Al-Ain University, Abu Dhabi Campus, Abu Dhabi, United Arab Emirates., Ali I; Department of Anthropology, Fatima Jinnah Women University, Rawalpindi, Pakistan., Malik ZI; Department of Public Health, Health Services Academy, Islamabad, Pakistan. |
| Abstrakt: |
Manganese is essential for adequate feto-maternal health; however, an inverted U-shaped relation has been found between maternal manganese status and pregnancy complications. This systematic review summarizes the effect of maternal manganese exposure and perinatal health. We adopted a systematic approach to retrieve the recent literature. After applying the inclusion/exclusion criterion, a total of 20 studies were included in this review. Results found a non-significant relationship between maternal manganese exposure and risk of gestational diabetes mellitus (GDM), while only three studies reported the association between higher manganese levels and risk of preterm birth. Also, inconsistent results were found regarding higher manganese status and risk of low birth weight. This review reported no association between higher maternal manganese status andrisk of GDM. Nevertheless, the paucity of literature related to small for gestational age and pre-eclampsia prohibits a conclusion. Further studies are required for evaluation of environmental manganese exposure and maternal manganese status. |
