Case management strategy enhances virological response in people living with human immunodeficiency virus in a resource-limited region in Southwest China: a real-world prospective observational study.

Autor: Song X; Mental Health Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China., Zheng J; Department of Outpatient, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China., Chen L; Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China. 14491291@qq.com., Ma F; Center of Antiretroviral Treatment, People's Hospital, Liangshan Yi Autonomous Prefecture, Zhaojue County, 616150, Sichuan, People's Republic of China., Li C; Center of Antiretroviral Treatment, People's Hospital, Liangshan Yi Autonomous Prefecture, Zhaojue County, 616150, Sichuan, People's Republic of China., Wang J; Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China., Du L; Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China., Tang H; Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China. htang6198@hotmail.com.
Jazyk: angličtina
Zdroj: AIDS research and therapy [AIDS Res Ther] 2024 Dec 18; Vol. 21 (1), pp. 91. Date of Electronic Publication: 2024 Dec 18.
DOI: 10.1186/s12981-024-00682-9
Abstrakt: This study assessed the effectiveness of case management compared to that of standard care in improving treatment outcomes for first-time antiretroviral therapy (ART) patients in Liangshan Prefecture, China. First-time ART patients (total n = 828) were divided into the Standard Care Group (SCG, n = 419) and Case Management Group (CMG, n = 409). At week 48, the CMG showed higher retention rates (97.7% vs. 93.6%), better adherence, and more complete virological responses (84.2% vs. 64.0%) compared to the SCG. These findings suggest that case management improves adherence and virological suppression in resource-limited areas, though further research is needed to confirm its broader applicability.
Competing Interests: Declarations. Ethics approval and consent to participate: The study received approval from the Medical Ethics Committee of West China Hospital, Sichuan University (Annual Review No. 450, version 2019.5). Informed consent was obtained from all participants. The study was retrospectively registered on 2023–09-28 (ChiCTR2300076265). Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.
(© 2024. The Author(s).)
Databáze: MEDLINE
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