Comment on: Toward an optimal contraception dosing strategy.

Autor: Benagiano G; Faculty of Medicine and Dentistry, 'Sapienza', University of Rome, Rome, Italy.; Geneva Foundation for Medical Education and Research, Geneva, Switzerland., Genazzani AR; Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, The University of Pisa, Pisa, Italy., Grandi G; Department of Medical and Surgical Sciences for Mother, Child and Adult, University of Modena and Reggio Emilia, Azienda Ospedaliero Universitaria Policlinico, Modena, Italy.aculty of Medicine, University of Modena, Modena, Italy., Guo SW; Department of Biochemistry and Molecular Biology, Research Institute of Shanghai Obstetrics & Gynecology Hospital, Fudan University, Shanghai, China., Habiba M; Department of Health Sciences, University of Leicester and University Hospitals of Leicester, Leicester, United Kingdom.
Jazyk: angličtina
Zdroj: PLoS computational biology [PLoS Comput Biol] 2024 Dec 18; Vol. 20 (12), pp. e1012398. Date of Electronic Publication: 2024 Dec 18 (Print Publication: 2024).
DOI: 10.1371/journal.pcbi.1012398
Abstrakt: The optimal contraception dosing strategy proposed by Gavina et al. recently is a commendable attempt to model a complex physiological process with potenial to apply to real-life data. However, there is a need to take into account the real challenges that arise when moving from the theory to its practical application, and it is important that lessons learnt from clinical studies be taken into consideration in any theoretical modelling. In this manuscript, we spell out these lessons and elaborate practical challenges facing their model.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 Benagiano et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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