Usefulness of Point-of-Care Testing for Respiratory Viruses in a Pediatric Emergency Department Setting.

Autor:	Bellini T; Paediatric Emergency Room and Emergency Medicine Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, via G. Gaslini, 5, 16147 Genoa, Italy., Fueri E; Paediatric Emergency Room and Emergency Medicine Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, via G. Gaslini, 5, 16147 Genoa, Italy., Formigoni C; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16147 Genoa, Italy., Mariani M; Infectious Diseases Unit and COVID Hospital, Department of Pediatrics, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy., Villa G; Paediatric Emergency Room and Emergency Medicine Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, via G. Gaslini, 5, 16147 Genoa, Italy., Finetti M; Paediatric Emergency Room and Emergency Medicine Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, via G. Gaslini, 5, 16147 Genoa, Italy., Marin M; Paediatric Emergency Room and Emergency Medicine Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, via G. Gaslini, 5, 16147 Genoa, Italy., De Chiara E; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16147 Genoa, Italy., Bratta A; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16147 Genoa, Italy., Vanorio B; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16147 Genoa, Italy., Casabona F; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16147 Genoa, Italy., Pepino C; Paediatric Emergency Room and Emergency Medicine Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, via G. Gaslini, 5, 16147 Genoa, Italy., Castagnola E; Infectious Diseases Unit and COVID Hospital, Department of Pediatrics, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy., Piccotti E; Paediatric Emergency Room and Emergency Medicine Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, via G. Gaslini, 5, 16147 Genoa, Italy., Moscatelli A; Pediatric and Neonatal Intensive Care Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.
Jazyk:	angličtina
Zdroj:	Journal of clinical medicine [J Clin Med] 2024 Dec 03; Vol. 13 (23). Date of Electronic Publication: 2024 Dec 03.
DOI:	10.3390/jcm13237368
Abstrakt:	Background : Respiratory tract infections (RTIs) are a leading cause of pediatric emergency department (PED) visits, especially in children under five. These infections are primarily viral, complicating diagnosis and management. This study assesses the impact of point-of-care (POC) rapid diagnostic tests for respiratory viruses on clinical and economic outcomes in a PED setting. Materials and Methods: A retrospective analysis of 1396 POC tests for RSV, adenovirus, and influenza A/B was conducted in the PED of the Giannina Gaslini Institute, Genoa, Italy, from December 2022 to April 2024. Demographics, blood tests, admissions, and readmission rates were evaluated. Statistical analyses were performed using appropriate tests for categorical and continuous variables. Results: Of the tests, 31.5% were positive for at least one virus. Positive patients were younger and had higher hospitalization rates (50.7% vs. 39.9%) but fewer blood tests (38.2% vs. 51.7%). Economic analysis indicated lower costs for virus-positive patients. RSV-positive patients showed a significant association with higher hospitalization rates (67.8%) and readmission within 72 h. Conclusions: POC testing significantly improves patient management in PEDs by enabling rapid diagnoses, reducing unnecessary tests and hospitalizations, and guiding appropriate treatment. This approach supports better resource allocation, crucial during peak seasons, and has implications for reducing antibiotic use and resistance. Further research is warranted to explore long-term impacts on patient outcomes and healthcare efficiency.
Databáze:	MEDLINE
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