Efficacy of Nonablative Bipolar Radiofrequency in the Treatment of Fingernail Psoriasis.

Autor: El-Basiony MAS; Department of Dermatology and Venereology, Medical Research and Clinical Studies Institute, National Research Centre, Giza, Egypt., El-Komy MHM; Department of Dermatology, Kasr Al-Ainy Psoriasis Unit, Faculty of Medicine, Cairo University, Giza, Egypt., Samy NA; Dermatology Unit, Department of Medical Applications of Lasers, National Institute of Laser Enhanced Sciences, Cairo University, Giza, Egypt; and., Aly DG; Department of Dermatology and Venereology, Medical Research and Clinical Studies Institute, National Research Centre, Giza, Egypt., El-Gendy H; Department of Internal Medicine and Rheumatology, Faculty of Medicine, Cairo University, Giza, Egypt., Soliman MM; Dermatology Unit, Department of Medical Applications of Lasers, National Institute of Laser Enhanced Sciences, Cairo University, Giza, Egypt; and., Abdel Salam Hassan MF; Department of Dermatology and Venereology, Medical Research and Clinical Studies Institute, National Research Centre, Giza, Egypt., El Sayed H; Department of Dermatology, Kasr Al-Ainy Psoriasis Unit, Faculty of Medicine, Cairo University, Giza, Egypt.
Jazyk: angličtina
Zdroj: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] [Dermatol Surg] 2024 Dec 16. Date of Electronic Publication: 2024 Dec 16.
DOI: 10.1097/DSS.0000000000004531
Abstrakt: Background: Psoriasis is a common chronic systemic disease affecting the skin, nails, and joints. Nails are commonly associated with a greater severity of the disease. Radiofrequency (RF) is a nonionizing radiation that provides energy originating from electric current to generate heat inside the dermis with anti-inflammatory effects.
Objective: To assess the efficacy of nonablative bipolar radiofrequency in treating fingernail psoriasis.
Methods: Forty-three affected fingernails were treated with nonablative bipolar RF. Sessions were performed every 2 weeks for 2 months, with a maximum of 5 sessions. The 32-point target nail psoriasis severity index (tNAPSI), ultrasonography, and the physicians' global assessment were used for assessment at baseline, 1 month, and 3 months from the last treatment session.
Results: One month after the last RF session, a significant reduction in median tNAPSI score from baseline was recorded (p = .002), with a 58.33% reduction in pit count. The median thickness of subungual hyperkeratosis decreased significantly from baseline (p = .024), and the median score of onycholysis was also significantly reduced (p = .005). Ultrasonography revealed a significant reduction in the median nail matrix, bed thickness, and nail vascularity (p = .020, p < .001, and p = .013, respectively).
Conclusion: Radiofrequency may offer a safe and effective treatment modality for fingernail psoriasis.
(Copyright © 2024 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.)
Databáze: MEDLINE