Framework for multi-stressor physiological response evaluation in amphibian risk assessment and conservation.

Autor:	Awkerman JA; Center for Ecosystem Measurement and Modeling, Office of Research and Development, US Environmental Protection Agency, Gulf Breeze, FL, United States., Glinski DA; Center for Ecosystem Measurement and Modeling, Office of Research and Development, US Environmental Protection Agency, Athens, GA, United States., Henderson WM; Center for Ecosystem Measurement and Modeling, Office of Research and Development, US Environmental Protection Agency, Athens, GA, United States., Van Meter R; Environmental Science and Studies, Washington College, Chestertown, MD, United States., Purucker ST; Center for Computational Toxicology and Exposure, Office of Research and Development, US Environmental Protection Agency, Durham, NC, United States.
Jazyk:	angličtina
Zdroj:	Frontiers in ecology and evolution [Front Ecol Evol] 2024 Mar 13; Vol. 12, pp. 1-16.
DOI:	10.3389/fevo.2024.1336747
Abstrakt:	Controlled laboratory experiments are often performed on amphibians to establish causality between stressor presence and an adverse outcome. However, in the field, identification of lab-generated biomarkers from single stressors and the interactions of multiple impacts are difficult to discern in an ecological context. The ubiquity of some pesticides and anthropogenic contaminants results in potentially cryptic sublethal effects or synergistic effects among multiple stressors. Although biochemical pathways regulating physiological responses to toxic stressors are often well-conserved among vertebrates, different exposure regimes and life stage vulnerabilities can yield variable ecological risk among species. Here we examine stress-related biomarkers, highlight endpoints commonly linked to apical effects, and discuss differences in ontogeny and ecology that could limit interpretation of biomarkers across species. Further we identify promising field-based physiological measures indicative of potential impacts to health and development of amphibians that could be useful to anuran conservation. We outline the physiological responses to common stressors in the context of altered functional pathways, presenting useful stage-specific endpoints for anuran species, and discussing multi-stressor vulnerability in the larger framework of amphibian life history and ecology. This overview identifies points of physiological, ecological, and demographic vulnerability to provide context in evaluating the multiple stressors impacting amphibian populations worldwide for strategic conservation planning. Competing Interests: Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Databáze:	MEDLINE
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