Comparison of Clinical and Pathological Characteristics of Thyroid Cancer Surgery in the Pandemic Era.

Autor:	Shafaeipour A; Department of General Surgery, Subdivision of Surgical Oncology, Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran., Shirkhoda M; Department of General Surgery, Subdivision of Surgical Oncology, Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran., Karami MY; Department of Surgical Oncology, Shiraz University of Medical Sciences, Shiraz, Iran., Moosaie F; Department of General Surgery, Subdivision of Surgical Oncology, Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.; International Surgical Research Association (ISRA), Universal Scientific Education and Research Network (USERN), Tehran, Iran., Jalaeefar A; Department of General Surgery, Subdivision of Surgical Oncology, Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran., Motiee-Langroudi M; Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran., Harirchi I; Department of General Surgery, Subdivision of Surgical Oncology, Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.
Jazyk:	angličtina
Zdroj:	Medical journal of the Islamic Republic of Iran [Med J Islam Repub Iran] 2024 Aug 28; Vol. 38, pp. 99. Date of Electronic Publication: 2024 Aug 28 (Print Publication: 2024).
DOI:	10.47176/mjiri.38.99
Abstrakt:	Background: The COVID-19 pandemic brought significant challenges for oncology centers and cancer patients, necessitating the implementation of various preventive and restrictive protocols and postponing elective surgeries. We aimed to assess and compare tumor characteristics, including the size, metastasis, and duration of hospitalizations between the periods before and during COVID-19 in patients with thyroid cancer. Methods: The present cross-sectional study was performed at The Institute of Cancer, Tehran University of Medical Sciences, with 143 patients observed 2 years before the pandemic and 92 during March 2020 and March 2022. Clinical and pathological tumor characteristics were compared between the 2 groups, including surgical details, hospitalization and intensive care unit (ICU) admission durations, time intervals between diagnoses and surgeries, and various metastatic factors. All data were analyzed using SPSS software 21. The chi-square test was used for the statistical analysis of qualitative data, and the t test was used for the statistical analysis of continuous data. P < 0.05 was considered statistically significant. Results: The most frequent tumor type was papillary thyroid cancer (134 [93.7%] and 82 [89.13%]; P = 0.209). The right lobe was the most prevalent tumor site both before and during COVID-19, respectively (55 [38.5%] and 29 [31.5%]; P = 0.278). Central (64 [50.8%] and 62 [49.2%]; P < 0.001), and lateral (45 [34.5%] and 45 [48.9 %]; P = 0.045) lymph node metastasis in the first surgery and recurrence ( P = 0.006 and P = 0.022, respectively) were significantly higher in patients admitted during the COVID-19 pandemic, respectively. The mean interval between the first surgery and subsequent surgery due to recurrence ( P < 0.001), duration of ICU admission ( P = 0.010), and hospitalization after the second operation were significantly lower during the pandemic ( P = 0.006). Conclusion: During the COVID-19 pandemic, patients exhibited larger tumors, increased lymph node metastasis, and shorter intervals between surgeries. This underscores the need for healthcare decision-makers to implement effective thyroid cancer management strategies in future outbreaks. Our study stands out by analyzing hospitalization and ICU admissions and duration for each patient, unlike any other study. Moreover, we extended our observation period beyond the typical duration found in most of the literature. Competing Interests: The authors declare that they have no competing interests. (© 2024 Iran University of Medical Sciences.)
Databáze:	MEDLINE
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