Insights into glymphatic system dysfunction and glucose continuum.

Autor: Velikova T; Medical Faculty, Sofia University St. Kliment Ohridski, Sofia 1407, Bulgaria., Vasilev G; Medical Faculty, Sofia University St. Kliment Ohridski, Sofia 1407, Bulgaria.; Clinic of Neurology and Department of Emergency Medicine, UMHAT 'Sv. Georgi', Plovdiv 4000, Bulgaria. vvasilev.georgi@gmail.com.
Jazyk: angličtina
Zdroj: World journal of diabetes [World J Diabetes] 2024 Dec 15; Vol. 15 (12), pp. 2404-2408.
DOI: 10.4239/wjd.v15.i12.2404
Abstrakt: In this article, we comment on an original article published in a recent issue of the World Journal of Diabetes . That observational cross-sectional study focused on investigating the function of the glymphatic system and its clinical correlates in patients with different glucose metabolism states by using diffusion tensor imaging along the perivascular space (DTI-ALPS) index. It was shown that the cerebral glymphatic system may be dysfunctional in patients with type 2 diabetes. Various clinical variables affected the DTI-ALPS index in different glucose metabolism states. In conclusion, the study by Tian et al improves the understanding of the pathophysiology of diabetes-associated brain damage and provides insights for early diagnosis.
Competing Interests: Conflict-of-interest statement: The authors declare no conflict of interest.
(©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.)
Databáze: MEDLINE