Mesalamine as treatment of neovaginal ileitis: Case report and review of literature.

Autor: King-Nakaoka EA; School of Medicine, University of Washington, Seattle, WA 98195, USA. Electronic address: elanakn@uw.edu., Yu LX; Department of Obstetrics and Gynecology, Pediatric and Adolescent Gynecology Division, University of Washington, Seattle, WA 98109, USA. Electronic address: lissayu@uw.edu.
Jazyk: angličtina
Zdroj: Journal of pediatric and adolescent gynecology [J Pediatr Adolesc Gynecol] 2024 Dec 12. Date of Electronic Publication: 2024 Dec 12.
DOI: 10.1016/j.jpag.2024.12.002
Abstrakt: Background: Neovaginal ileitis is an understudied complication of intestinal vaginoplasty for which no evidence-based treatments exist. Mesalamine has been successfully reported to treat neovaginal colitis and has mixed evidence of efficacy in treating ileal inflammatory syndromes.
Case: We report a 29-year-old female with a history of ileal neovaginoplasty at two years of age for cloacal variant and treatment-refractory neovaginal ileitis with pain and bleeding whose symptoms resolved with treatment with topical mesalamine.
Conclusion: Mesalamine may be a viable treatment for neovaginal ileitis. More data is needed on neovaginal ileitis incidence and treatment, in addition to broader quality of life outcomes after intestinal vaginoplasty.
(Copyright © 2024. Published by Elsevier Inc.)
Databáze: MEDLINE
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