Is COVID-19 infection during pregnancy a risk for congenital hearing loss?

Autor: Sheehan J; Centre for Community Child Health, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia; Murdoch Children's Research Institute, Parkville, Victoria, Australia. Electronic address: jane.sheehan3@rch.org.au., Jagger A; Centre for Community Child Health, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia; Murdoch Children's Research Institute, Parkville, Victoria, Australia. Electronic address: alison.jagger@rch.org.au., Francis KL; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia. Electronic address: kate.francis@mcri.edu.au., Dashti SG; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia. Electronic address: ghazaleh.dashti@mcri.edu.au., Gornall P; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia. Electronic address: pgornall@student.unimelb.edu.au., Barker M; Centre for Community Child Health, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia. Electronic address: melinda.barker@rch.org.au., Sung V; Centre for Community Child Health, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia. Electronic address: valerie.sung@rch.org.au., Ruiz-Carmona S; Centre for Health Analytics, Melbourne Children's Campus, Melbourne, Victoria, Australia. Electronic address: sergio.ruizcarmona@rch.org.au., Baohm S; Centre for Health Analytics, Melbourne Children's Campus, Melbourne, Victoria, Australia. Electronic address: susan.baohm2@rch.org.au., Poulakis Z; Centre for Community Child Health, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia; Murdoch Children's Research Institute, Parkville, Victoria, Australia; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia. Electronic address: zeffie.poulakis@rch.org.au.
Jazyk: angličtina
Zdroj: International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2024 Dec 09; Vol. 188, pp. 112191. Date of Electronic Publication: 2024 Dec 09.
DOI: 10.1016/j.ijporl.2024.112191
Abstrakt: Objective: Infections during pregnancy can increase the risk of congenital hearing loss. This population-based study investigated the effect of birthing parent COVID-19 infection during pregnancy on risk of congenital hearing loss in infants.
Methods: Records of infants born in 2022 were reviewed via a retrospective clinical audit of a universal state-wide newborn hearing screening program in Victoria, Australia. The number and timing of COVID-19 infections during pregnancy were collected via self-report at the time of the hearing screen. Infant records (n = 75,330) were divided into birthing parent infection group (n = 25,547, 33.9 %), and non-infection group (n = 49,783, 66.1 %). Group differences in screen and diagnostic audiology results were estimated by general linear regression models with a binomial distribution.
Results: Birthing parent and infant characteristics were similar across groups. Comparable proportions of infants obtained a refer result on their newborn hearing screen, requiring referral to diagnostic audiology (infection group: 1.4 %, 95%CI 1.2-1.5 versus non-infection group: 1.3 %, 95%CI 1.2-1.4). The proportion of infants diagnosed with any type and degree of hearing loss was also similar (infection group: 0.6 %, 95%CI 0.5-0.7 versus non-infection group: 0.6 %, 95%CI 0.6-0.7).
Conclusion: This epidemiological study is the largest to date and demonstrates that infants whose birthing parent reported COVID-19 infection during pregnancy were not at increased risk of obtaining a refer result on their newborn hearing screen, nor at increased risk of congenital hearing loss. Specific protocols or guidelines to manage the newborn hearing screening pathway of infants born to a parent with COVID-19 during pregnancy are not supported by this study's findings.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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