Untargeted qualitative and targeted quantitative analysis of saponins reveal differential chemotypes of Gynostemma pentaphyllum and G. longipes from different geographical origins.

Autor: Liang HZ; Beijing Institute of Radiation Medicine, Beijing 100850, China., Wang MY; Beijing Institute of Radiation Medicine, Beijing 100850, China; Guangdong Pharmaceutical University, Guangzhou 510060, China., Yang G; Beijing Institute of Radiation Medicine, Beijing 100850, China., Li G; Beijing Institute of Radiation Medicine, Beijing 100850, China., Zhang J; Beijing Institute of Radiation Medicine, Beijing 100850, China., Yao L; Beijing Institute of Radiation Medicine, Beijing 100850, China., Nan Y; Beijing Institute of Radiation Medicine, Beijing 100850, China., Huang CL; Beijing Institute of Radiation Medicine, Beijing 100850, China; Guangdong Pharmaceutical University, Guangzhou 510060, China., Chen XJ; Beijing Institute of Radiation Medicine, Beijing 100850, China., Song J; Beijing Institute of Radiation Medicine, Beijing 100850, China., Cao F; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China., Guo BL; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China., Ma BP; Beijing Institute of Radiation Medicine, Beijing 100850, China. Electronic address: mabaiping@sina.com.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2024 Dec 09; Vol. 468, pp. 142412. Date of Electronic Publication: 2024 Dec 09.
DOI: 10.1016/j.foodchem.2024.142412
Abstrakt: Jiaogulan herbal tea, known for its pharmacological benefits, is derived from various species within the genus Gynostemma, particular for G. pentaphyllum (GP) and G. longipes (GL). Herein, a global approach integrating chemometrics with qualitative and quantitative methods was utilized to investigate the chemical profiles and variations in GP and GL from different geographic origins. A total of 227 triterpenoid saponins were identified in two Gynostemma species, among which 23 differential markers ware screened out by multivariate statistical analysis. Furthermore, the contents of significant markers were determined after the demalonylation process. The chemical composition of GP samples sourced from diverse regions were firstly summarized into three chemotypes (I-III), along with an additional chemotype (IV) for GL. This study contributes to a deeper understanding of Gynostemma plants and provides valuable theoretical basis for the quality control in the production of Jiaogulan herbal tea.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024. Published by Elsevier Ltd.)
Databáze: MEDLINE
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