Acidic hydrothermal processing of wheat using citrate buffer largely enhances iron and zinc bioaccessibility and bioavailability to Caco-2 cells.

Autor: Huyskens M; Laboratory of Food Chemistry and Biochemistry, KU Leuven, Belgium. Electronic address: marie.huyskens@kuleuven.be., Lemmens E; Laboratory of Food Chemistry and Biochemistry, KU Leuven, Belgium. Electronic address: elien.lemmens1@kuleuven.be., Grootaert C; Laboratory of Food Chemistry and Human Nutrition, UGent, Belgium. Electronic address: charlotte.grootaert@ugent.be., Van Camp J; Laboratory of Food Chemistry and Human Nutrition, UGent, Belgium. Electronic address: john.vancamp@ugent.be., Verbeke K; Laboratory of Digestion and Absorption, KU Leuven, Belgium. Electronic address: kristin.verbeke@kuleuven.be., Goos P; Department of Biosystems, Division of Mechatronics, KU Leuven, Belgium. Electronic address: peter.goos@kuleuven.be., Smolders E; Division of Soil and Water Management, KU Leuven, Belgium. Electronic address: erik.smolders@kuleuven.be., Delcour JA; Laboratory of Food Chemistry and Biochemistry, KU Leuven, Belgium. Electronic address: jan.delcour@kuleuven.be.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2024 Dec 04; Vol. 467, pp. 142340. Date of Electronic Publication: 2024 Dec 04.
DOI: 10.1016/j.foodchem.2024.142340
Abstrakt: Phytate chelates iron (Fe) and zinc (Zn) in wheat. A multifactorial experiment showed that hydrothermal processing (45-60 °C, pH 4.0-6.0, 8-24 h) of wheat using acetate or lactate buffers reduced phytate contents by a factor 1.4 to 2.8 and increased bioaccessibility, determined with an in vitro digestion, maximally 1.9 (Fe) or 1.5 (Zn) times relative to unprocessed wheat. In contrast, hydrothermal processing using citrate buffer reduced phytate contents by a factor 1.3 to 2.0 and increased bioaccessibility values 9.8 (Fe) and 8.8 (Zn) times, due to formation of soluble chelates. The in vitro digests were supplied to Caco-2 cells, showing that mineral bioavailabilities in these processed wheat grains were 6-fold (Fe) and 12-fold (Zn) higher than in unprocessed wheat. Thus, hydrothermal processing of wheat using citrate buffer can be used for developing whole grain-based products with increased Fe and Zn bioavailability.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. This research was conducted in the framework of the W.K. Kellogg Chair in Cereal Science at the KU Leuven (chair holders J. A. Delcour and K. Verbeke).
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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