Oral surgery complication resulting from undiagnosed common variable immunodeficiency: a case report.

Autor: Mezaiko E; Universidade Federal de Goiás, Goiânia, Brazil. eleazarmezaiko@gmail.com., Teixeira Brito L; Governor Otávio Lage de Siqueira State Emergency Hospital, Goiânia, Brazil., Britto Cançado BL; Pontifícia Universidade Católica de Goiás, Goiânia, Brazil., da Silva Junior WF; Pontifícia Universidade Católica de Goiás, Goiânia, Brazil., Yamamoto-Silva FP; Universidade Federal de Goiás, Goiânia, Brazil.; Centro Universitário de Anápolis, Anápolis, Brazil., de Freitas Silva BS; Universidade Federal de Goiás, Goiânia, Brazil.; Centro Universitário de Anápolis, Anápolis, Brazil.
Jazyk: angličtina
Zdroj: Oral and maxillofacial surgery [Oral Maxillofac Surg] 2024 Dec 12; Vol. 29 (1), pp. 20. Date of Electronic Publication: 2024 Dec 12.
DOI: 10.1007/s10006-024-01310-6
Abstrakt: Purpose: This report aims to present an interdisciplinary approach to diagnosing and treating a case of Common Variable Immunodeficiency (CVID), an inborn error of immunity, resulting in successive complications following a third molar extraction procedure.
Case Presentation: The patient, a 37-year-old Caucasian female, sought a specialist for the extraction of an impacted lower third molar associated with dentigerous cyst. Due to the possibility of mandibular fracture, a bone fixation system was used in the region. However, she experienced recurrent infections following the procedure despite various treatments and hospitalizations, and these infections could not be explained by any factors. The diagnosis of CVID was established through exclusionary factors, low immunoglobulin levels, and comprehensive allergy assessments by an immunologist. Resolution of the patient's condition and discharge were achieved only after removing the fixation system and implementing monthly immunoglobulin infusions.
Conclusion: CVID is often diagnosed late, resulting in significant economic, social, and health burdens, including recurrent hospitalizations, allergies, and increased risk of malignancy. This case underscores the importance of considering CVID in patients presenting with unexplained recurrent infections following oral and maxillofacial surgeries. Additionally, it highlights the necessity of a multidisciplinary approach for effectively managing patients with CVID.
Competing Interests: Declarations. Ethical approval: The patient signed the free and informed consent form for the treatment and for the scientific dissemination of the case. Competing interests: The authors declare no competing interests.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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