Insufficiency of Laboratory Data in Reflecting Allergic Rhinitis Severity Based on the Allergic Rhinitis and Its Impact on Asthma Guideline in Korean Patients.

Autor:	Noh HE; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea., Jeong Y; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea., Rha MS; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim CH; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.; The Airway Mucus Institute, Yonsei University College of Medicine, Severance Hospital, Seoul, Republic of Korea., Cho HJ; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.; The Airway Mucus Institute, Yonsei University College of Medicine, Severance Hospital, Seoul, Republic of Korea.
Jazyk:	angličtina
Zdroj:	Journal of rhinology : official journal of the Korean Rhinologic Society [J Rhinol] 2024 Mar; Vol. 31 (1), pp. 17-21. Date of Electronic Publication: 2024 Mar 31.
DOI:	10.18787/jr.2023.00066
Abstrakt:	Background and Objectives: This retrospective study, conducted at a single tertiary medical center, aimed to investigate the correlation between the severity of allergic rhinitis (AR) based on subjective symptoms and the severity assessed through laboratory data. Methods: In total, 584 patients who were diagnosed with AR by a multiple-allergen simultaneous test were included. Patients were classified into four groups according to the Allergic Rhinitis and its Impact on Asthma (ARIA) classification guideline. The visual analog scale (VAS) score for overall discomfort and laboratory parameters, including the serum total immunoglobulin E (IgE) level and peripheral blood eosinophil count, were evaluated in all patients. An analysis was conducted to examine the differences in VAS scores and laboratory findings among the four groups. Additionally, the correlations between the laboratory findings and VAS score were analyzed. Results: The serum total IgE level and the percentage and count of peripheral blood eosinophils showed no significant differences among the groups. However, the VAS score for overall discomfort exhibited notable between-group differences. The average VAS score was 6.14 (95% confidence interval 5.94-6.34) in the overall group. The mean scores of each group showed a noticeable increasing trend from the mild intermittent group to the mild persistent, moderate to severe intermittent, and moderate to severe persistent groups (p<0.001), although there was no clear correlation between the increase in VAS scores and laboratory parameters. Conclusion: Neither the symptom-based ARIA guideline nor the VAS score correlated with the AR laboratory test measurements. The current laboratory data alone may not be sufficient to reflect the severity of AR based on subjective symptoms. Competing Interests: Conflicts of Interest The authors have no potential conflicts of interest to disclose. (Copyright © 2024 by The Korean Rhinologic Society.)
Databáze:	MEDLINE
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