Fatigue, impaired physical function and mental health in cancer survivors: the role of social isolation.

Autor: Kittel JA; Department of Public Health Sciences, University of Rochester School of Medicine and Dentistry, 265 Crittenden Blvd, CU 420644, Rochester, NY, 14642, USA. julie.kittel-moseley@va.gov., Seplaki CL; Department of Public Health Sciences, University of Rochester School of Medicine and Dentistry, 265 Crittenden Blvd, CU 420644, Rochester, NY, 14642, USA.; Department of Psychiatry, University of Rochester Medical Center, Rochester, NY, USA., van Wijngaarden E; Department of Public Health Sciences, University of Rochester School of Medicine and Dentistry, 265 Crittenden Blvd, CU 420644, Rochester, NY, 14642, USA., Richman J; Department of Psychiatry, University of Rochester Medical Center, Rochester, NY, USA., Magnuson A; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA., Conwell Y; Department of Psychiatry, University of Rochester Medical Center, Rochester, NY, USA.
Jazyk: angličtina
Zdroj: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer [Support Care Cancer] 2024 Dec 11; Vol. 33 (1), pp. 16. Date of Electronic Publication: 2024 Dec 11.
DOI: 10.1007/s00520-024-09075-0
Abstrakt: Purpose: Cancer survivors experience an array of physical, psychological, and social problems after treatment has ended. Perceived social isolation may exacerbate the effects of physical problems on mental health. We examined the association between physical health (cancer-related fatigue and physical function) and mental health (depression and anxiety symptoms) in cancer survivors in the first year of survivorship (i.e., up to one year after the end of treatment with curative intent), as well as the moderating role of perceived social isolation.
Methods: Survey data were collected from 118 cancer survivors who completed treatment with curative intent in the last year. We assessed mental and physical health symptoms, as well as perceived social isolation.
Results: In multivariable analyses, fatigue was significantly associated with both depression (β = 0.279, 95% CI: 0.193,0.362) and anxiety symptoms (β = 0.189, 95% CI: 0.106,0.272). Social isolation moderated the effect of fatigue on depression and anxiety such that higher social isolation exacerbated the association of fatigue with mental health.
Conclusions: Cancer survivors who continue to experience fatigue after curative treatment are at risk for mental health problems, including depression and anxiety symptoms. For cancer survivors who feel socially isolated, the association between fatigue and mental health may be stronger. The current standard of care for survivorship does not sufficiently address psychosocial needs. Future research should evaluate the inclusion of social support interventions in early-term survivorship care.
Competing Interests: Declarations. Ethics approval: This study was conducted in line with the Declaration of Helsinki. The questionnaire and methodology for this study was approved by the University of Rochester Medical Center Research Subjects Review Board (Study #5302) and the University of Rochester Wilmot Cancer Institute Protocol Review and Monitoring Committee (UCCS20104). Consent to participate: Informed consent was obtained from all individual participants included in the study. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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