Establishment of a brain tumor consortium of Africa: Advancing collaborative research and advocacy for brain tumors in Africa.

Autor:	Odukoya LA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, New York, USA., Darko K; Department of Neurosurgery, Korle-Bu Teaching Hospital, Accra, Ghana., Zerd F; Mortuary and Forensic Department, Benjamin Mkapa Hospital, Dodoma, Tanzania., Ghomsi NC; Department of Neurosurgery, Université Félix Houphouet Boigny, Abidjan, Côte d'Ivoire., Kabare G; Neurosurgery Department, Aga Khan University Hospital, Nairobi, Kenya., Kamson DO; Department of Oncology and Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA., Eckel-Passow JE; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, New York, USA., Jenkins RB; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, New York, USA., Kitange GJ; Division of Neuro-Oncology Research, The Hormel Institute, University of Minnesota, Austin, Minnesota, USA., Akinjo AO; Anatomic and Molecular Pathology, Lagos University Teaching Hospital, Lagos, Nigeria., Badmos KB; Anatomic and Molecular Pathology, Lagos University Teaching Hospital, Lagos, Nigeria., Bankole O; Neurosurgery Unit, Department of Surgery, College of Medicine, University of Lagos, Lagos, Nigeria., Idowu OE; Neurosurgery Unit, Department of Surgery, Lagos State University Teaching Hospital and Lagos State University College of Medicine Ikeja, Lagos, Nigeria., Karekezi C; Neurosurgery Unit, Department of Surgery, Rwanda Military Referral and Teaching Hospital, University of Rwanda, Kigali, Rwanda., Edrick E; Department of Pathology, Catholic University of Health and Allied Sciences, Mwanza, Tanzania., Ekhator C; Department of Neuro-Oncology, New York Institute of Technology, College of Osteopathic Medicine, New York, New York, USA., Katasi VM; Department of Pediatric Oncology and Hematology, Mulago National Referral Hospital, Mulago, Uganda., Brown DA; Department of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA., Huse J; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Llewellyn H; Department of Global Health & Social Medicine, King's College London, London, UK., Magambo M; Department of Radiology, Bugando Medical Centre, Mwanza, Tanzania., Magoha M; Department of Surgery, University of Nairobi, Nairobi, Kenya., Barrie U; Department of Neurosurgery, NYU Grossman School of Medicine, New York, New York, USA., Ngaiza A; Department of Anatomical Pathology, Muhimbili National Hospital, Muhimbili, Tanzania., Nyalundja AD; Center for Tropical Diseases and Global Health, Faculty of Medicine, Université Catholique de Bukavu, Bugabo, Democratic Republic of Congo., Okemwa M; Department of Human Pathology, University of Nairobi, Nairobi, Kenya., Osei-Tutu L; Paediatric Oncology Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana., Petershie B; Department of Pathology, Komfo Anokye Teaching Hospital, Kumasi, Ghana., Yevudza WE Jr; Department of Neurosurgery, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA., Anunobi CC; Anatomic and Molecular Pathology, Lagos University Teaching Hospital, Lagos, Nigeria., Tiamiyu L; Department of Neurological Surgery, Federal Medical Centre, Abeokuta, Nigeria., Gankpe GF; Department of Neurosurgery, Centre National Hospitalier Universitaire Hubert Koutoukou, Cotonou, Benin., Heronima K; Department of Oncology, Bugando Medical Centre, Mwanza, Tanzania., Higgins D; Department of Neurosurgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Schroeder K; Pediatric Oncology, Bugando Medical Centre, Mwanza, Tanzania., Totimeh T; Department of Surgery, Accra Medical Centre, Accra, Ghana., Balogun J; Division of Neurosurgery, Department of Surgery, College of Medicine, University of Ibadan, Ibadan, Nigeria., Cheserem B; Neurosurgery Department, Aga Khan University Hospital, Nairobi, Kenya., Etame AB; Department of Neuro-Oncology, Moffitt Cancer Centre, University of South Florida, Tampa, Florida, USA., Fonkem E; Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconson, USA.
Jazyk:	angličtina
Zdroj:	Neuro-oncology advances [Neurooncol Adv] 2024 Nov 16; Vol. 6 (1), pp. vdae198. Date of Electronic Publication: 2024 Nov 16 (Print Publication: 2024).
DOI:	10.1093/noajnl/vdae198
Abstrakt:	Background: Brain tumors represent a significant global health challenge, with rising incidence and mortality impacting individuals worldwide and contributing to cancer-related morbidity and mortality. In Africa, this burden is exacerbated by limited access to advanced diagnostics, treatment options, and multidisciplinary care, compounded by the absence of standardized cancer registration and tumor biobanking. The introduction of molecular diagnostics, as outlined in the 2021 World Health Organization central nervous system (CNS) tumor classification, adds complexity to brain tumor management, particularly in regions with scarce resources. Methods: To address these issues, the Brain Tumor Consortium for Africa (BTCA) was established in 2023, bringing together experts to improve CNS tumor diagnosis, patient care, and research. The initial project, conducted via an electronic questionnaire, aimed to assess neuro-oncology capacity across Sub-Saharan Africa. Results: The study revealed significant gaps, with a limited number of institutions incorporating molecular subtyping into their diagnostic algorithms. The consortium's efforts focus on enhancing local data use, informing public policy, and promoting collaboration to advance neuro-oncology practices in Africa. By fostering a network enlisting the expertise of collaborators in the fields of neurosurgery, neurology, neuropathology, anatomic pathology, and medical and radiation oncology, the BTCA seeks to improve brain tumor management through better diagnostics, infrastructure, and policy advocacy. Future directions include expanding molecular diagnostic capabilities, standardizing brain tumor biobanking, enhancing data collection, and advocating for improved brain tumor care in national health agendas. Conclusions: The BTCA represents a pioneering model of collaboration and innovation in addressing the unique challenges of brain tumor care in Africa. Competing Interests: The authors have no personal or institutional interest with regard to the authorship and/or publication of this manuscript. (© The Author(s) 2024. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.)
Databáze:	MEDLINE
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