Oral Verruciform Xanthoma of the Lower Lip: A Rare Entity.
| Autor: | Chatterjee A; Oral and Maxillofacial Pathology, Buddha Institute of Dental Sciences and Hospital, Patna, IND., Purkait SK; Oral and Maxillofacial Pathology, Buddha Institute of Dental Sciences and Hospital, Patna, IND., Banerjee I; Pediatric and Preventive Dentistry, Guru Nanak Institute of Dental Sciences & Research, Kolkata, IND., Banerjee A; Oral and Maxillofacial Pathology, Awadh Dental College and Hospital, Jamshedpur, IND., Ramalingam K; Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Nov 09; Vol. 16 (11), pp. e73352. Date of Electronic Publication: 2024 Nov 09 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.73352 |
| Abstrakt: | Oral verruciform xanthoma (OVX) is a rare entity, and only a handful of cases have been reported in the literature to date. This innocent-looking lesion can mimic any benign epithelial or connective tissue origin neoplasm. It can present with variations in surface color and texture. Cases have been reported in intra-osseous and extra-osseous sites, mainly in masticatory mucosa and very few in non-keratinized mucosal sites. Literature suggests the xanthoma cells possess a monocyte/macrophage lineage, although the exact etiopathogenesis remains unclear. Our patient was a 20-year-old male who presented with a soft, keratotic growth in the lower lip. It clinically mimicked a mucocele or a traumatic fibroma until the mystery was resolved by histopathology and immunohistochemistry. Histopathology revealed numerous foamy, granular xanthoma cells in the stroma along with inflammation and hyperplastic epithelium. Immunohistochemistry showed positivity to CD68 and Cathepsin-B but negative to S-100. The final diagnosis was made as oral verruciform xanthoma. It was surgically excised and remained recurrence-free on follow-up. Competing Interests: Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Chatterjee et al.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|