Microscope-Integrated OCT-Assisted Real-time Monitoring of Central Corneal Thickness During Corneal Cross-linking.
| Autor: | Sushma N, Sharma S, Bari A, Agarwal T, Dada T, Sharma N |
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| Jazyk: | angličtina |
| Zdroj: | Journal of refractive surgery (Thorofare, N.J. : 1995) [J Refract Surg] 2024 Dec; Vol. 40 (12), pp. e934-e940. Date of Electronic Publication: 2024 Dec 01. |
| DOI: | 10.3928/1081597X-20241021-02 |
| Abstrakt: | Purpose: To assess real-time intraoperative pachymetry changes occurring during corneal cross-linking (CXL) using microscope-integrated optical coherence tomography (Mi-OCT) and compare accuracy of various modalities of pachymetry assessment. Methods: This was a cross-sectional observational comparative study including 45 consecutive patients with progressive keratoconus planned for CXL. Mi-OCT (RESCAN 700) was used to measure central corneal thickness (CCT) during four stages of CXL: before epithelial debridement, after debridement, after riboflavin instillation, and after ultraviolet irradiation. Scheimpflug imaging, anterior segment OCT (AS-OCT), and ultrasound pachymetry were used to assess CCT preoperatively. All data were entered into Excel software (Microsoft Corporation) and analyzed. Results: The CCT significantly decreased after each step of CXL as measured on Mi-OCT ( P < .0001). Mi-OCT overestimated the CCT significantly by 1.12 times on average (range: 1.02 to 1.43) compared to ultrasound pachymetry ( P = .0004). CCT measured using Scheimpflug imaging and anterior segment OCT was statistically comparable to ultrasound pachymetry. Conclusions: Mi-OCT provides a real-time assessment of CCT during CXL. However, because it overestimates the pachymetry, ultrasound pachymetry remains the gold standard for decision-making during CXL. [ J Refract Surg . 2024;40(12):e934-e940.] . Competing Interests: Disclosure: The authors have disclosed no potential conflicts of interest, financial or otherwise. |
| Databáze: | MEDLINE |
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